Name | 5-(2-aminoethylamino)-1-naphthalene-*sulfonic aci |
Synonyms | EDANS 1,5-EDANS EDANS ACID N-(AMINOETHYL)-5-NAPHTHYLAMINE-1-SULFONIC ACID 5-(2-AMINOETHYLAMINO)-1-NAPHTHALENE SULFONIC ACID N-(2-AMINOETHYL)-5-NAPHTHYLAMINE-1-SULPHONIC ACID 5-(2-aminoethylamino)-1-naphthalene-*sulfonic aci 5-((2-AMINOETHYL)AMINO)NAPHTHALENE-1-SULFONIC ACID |
CAS | 50402-56-7 |
EINECS | 256-575-5 |
InChI | InChI=1/C12H14N2O3S/c13-7-8-14-11-5-1-4-10-9(11)3-2-6-12(10)18(15,16)17/h1-6,14H,7-8,13H2,(H,15,16,17) |
Molecular Formula | C12H14N2O3S |
Molar Mass | 266.32 |
Density | 1.432±0.06 g/cm3(Predicted) |
Melting Point | >350°C |
Solubility | Aqueous Base (Slightly), DMSO (Slightly, Heated) |
Appearance | Solid |
Color | Yellow to Beige |
pKa | -0.37±0.40(Predicted) |
Storage Condition | Refrigerator |
Refractive Index | 1.691 |
In vitro study | The peptide sequence of EDANS is derived from a natural processing site for HIV-1 PR.Incubation of recombinant HIV-1 PR with the fluorogenic substrate resulted in specific cleavage at the Tyr-Pro bond and a time-dependent increase in fluorescence intensity that was linearly related to the extent of substrate hydrolysis. |
Hazard Symbols | Xn - Harmful |
Risk Codes | R22 - Harmful if swallowed R36/37/38 - Irritating to eyes, respiratory system and skin. R43 - May cause sensitization by skin contact |
Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S27 - Take off immediately all contaminated clothing. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) |
WGK Germany | 3 |
Biological activity | EDANS (1,5-EDANS) is a new type of quenched fluorescent substrate (fluorogenic substrate) for the analysis of retroviral proteases through resonance energy transfer. |